Pharmacogenomics perspective for forensic toxicology: A mini review

نویسندگان

چکیده

Pharmacogenetic and Pharmacogenomics are the study of association between an individual's genotype their response to xenobiotics Pharmacokinetic pharmacodynamics variations can appear at level drug-metabolizing enzymes, drug transporters, targets or other biomarker genes. can, therefore, be relevant in forensic toxicology. This review presents aspects together with some examples from daily routines. Use pharmacogenomics toxicology may add understanding toxicity due genetically predisposed impaired metabolism provide findings which back-extrapolated for benefits optimization antemortem therapy.

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ژورنال

عنوان ژورنال: Medicine Science | International Medical Journal

سال: 2022

ISSN: ['2147-0634']

DOI: https://doi.org/10.5455/medscience.2022.07.165